Rotavirus is a highly contagious virus that can primarily affect infants and young children, known to be one of the leading causes of severe diarrhea in children worldwide. Rotavirus is primarily known to be transmitted through the faecal-oral route, and contaminated water can be a significant source of its transmission if not attended to and treated correctly. In certain regions with inadequate sanitation and hygiene practices, rotavirus can contaminate water sources, such as rivers, lakes, ponds or wells, which can occur when sewage or faecal matter contain the virus enters the water supply. In this instance, certain specific submicron water filtration cartridges and UV sterilization systems can be capable and successful in the reduction and removal of such viruses, leaving the water free from transmission.